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Trysa Shulman's avatar

I would love to hear more about how thoughtful psychiatrists approach prescribing for patients who have done well on lithium for years after initial manic psychosis and severe depressions, are stable and get regular lithium level tests, and are experiencing signs of renal failure.

Awais Aftab's avatar

Because renal impairment tends to progress with continued lithium use, the general approach in patients who are heading towards renal failure is to try to substitute with a different mood stabilizing medication. Some patients do unfortunately decompensate in the process. Many are able to figure out a workable substitute regimen. Those who can’t do well without lithium, they and their doctors face a difficult choice between a rock and a hard place

Mat Poehler's avatar

Thanks for writing about this medicine. I have never on Lithium, but have always been told of its efficacy.

Dvir Caspi's avatar

As someone from Modi'in, Israel never thought I would come across modiin in this substack. Thanks for covering this topic

Chris's avatar

Thank you very much for this extensive summary.

Poems from Your Mother's avatar

Such an interesting read. I would love to hear group thoughts on using subclinical blood level dosing for patients with mood lability or dysthymia or over the counter supplement with lithium oratate or lithium combined with ascorbic acid? So many questions to still explore.