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Eric Caplan's avatar

David, I accept your critique. I weighed whether to keep the metaphorical pairing, mindful of Ronald Pies's compelling analysis (https://www.psychiatrictimes.com/view/debunking-two-chemical-imbalance-myths-again). I also had little doubt I'd be challenged — though not, I confess, by the very first comment posted on Awais's blog mere moments after the interview appeared. :)

I'm fine with that.

I don't dispute Pies's framing. What I dispute are the inferences that you and others draw from it, which strike me as implausible: namely, that a majority, or even a significant plurality, of psychiatrists have not embraced the metaphor. I think they have. Not that there's anything wrong with that. Cardiologists know there's no such thing as "good" and "bad" cholesterol. Oncologists know — I imagine, at least — that one cannot wage a "war on cancer." Indeed, William James, more than a century ago, introduced MEOW (Moral Equivalent of War), or so I think. But I could be mistaken. Pies may well be right about the commercial origins of "chemical imbalance," but being right about that strikes me as more scholastic than illuminating.

I suspect if we had a chance to speak, we'd enjoy the exchange. Have a great weekend. And buy the book and let me know what you think.*

David Bresch MD's avatar

This is a marvelous discussion and I heartily approve of its focus and approach but in that spirit I can’t let the offhand comment about “chemical imbalance”, pass. Where in hell did you get that from? I expect a remark like that on Tictoc but not from an erudite scholar. What text or research promotes this absurd idea? I have been practicing psychiatry for twenty five years. I hold three board certifications in areas central to current neuroscience. Never once have I come across this formulation in any scientific text or paper. To me it’s a sort of joke.

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