Psychiatry at the Margins
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Clinical Staging, Early Intervention, and Youth Mental Health: An Interview with Patrick McGorry
How do we intelligently connect multifactorial, pluripotential syndromes to treatment decisions?
Feb 13
•
Awais Aftab
36
5
7
What Do We Owe the Insufferable?
When mental illness exhausts our emotional capacities
Jan 30
•
Awais Aftab
326
9
74
ADHD Beyond Stimulants, and Stimulants Beyond ADHD
Your brain on stimulants vs your brain on ADHD
Jan 24
•
Awais Aftab
270
13
34
Most Popular
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DSM Disorders Disappear in Statistical Clustering of Psychiatric Symptoms
Mar 9, 2024
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Awais Aftab
374
6
59
Autism’s Confusing Cousins
Dec 5, 2025
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Awais Aftab
247
19
40
What Do We Owe the Insufferable?
Jan 30
•
Awais Aftab
326
9
74
Confessions of an Ambivalent Psychiatrist
Feb 1, 2025
•
Susan T. Mahler, MD
335
15
59
ADHD Beyond Stimulants, and Stimulants Beyond ADHD
Jan 24
•
Awais Aftab
270
13
34
Schizophrenia Is the Price We Pay for Minds Poised Near the Edge of a Cliff
May 10, 2025
•
Awais Aftab
122
5
33
Latest
Top
Discussions
Reconsidering Lithium as the Gold Standard for Bipolar Disorder: A Personal History
“Lithium is one of our tools but has no special status.”
Jan 17
•
Haim Belmaker
55
24
13
Can a Psychiatric Crisis Save Your Life?
Madness as breakdown and breakthrough
Jan 10
•
Awais Aftab
130
28
26
Notable Links (Substack Edition) - Jan 3, 2026
And some personal media favorites from 2025
Jan 3
•
Awais Aftab
65
7
13
The All of Thine That Cannot Die: Farewell to Two Friends
In memory of Dan J. Stein and Lisa Wallace
Dec 29, 2025
•
Awais Aftab
53
17
8
How the Citrus Cure for Scurvy Was Lost, and Lessons for the Science of Psychopathology
The copper-lined containers and the contexts that neutralize treatment
Dec 26, 2025
•
Awais Aftab
81
9
21
Antipsychotic tapering appears to help long-term in a new trial but not for the obvious reason
And considerable uncertainty remains
Dec 18, 2025
•
Awais Aftab
47
17
7
Mixed Bag #25: Kinnon MacKinnon on Trans Identity and Medicine
a book, a concept, a person, an article, and a surprise item
Dec 13, 2025
•
Kinnon Ross MacKinnon
39
2
11
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Psychiatry at the Margins
Exploring critical, philosophical, and scientific debates in psychiatric practice and the psy-sciences
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